Jamie Madrox (born James Spaniolo, November 5, 1975) is an American rapper from Detroit, Michigan and performs as a member of the rap group Twiztid. Spaniolo’s stage name is a reference to Marvel Comics’s character Multiple Man.
Madrox has been a mainstay in the underground wicked shit scene for decades and has been a part of many influential groups including House of Krazees, Dark Lotus, the Psychopathic Rydas, and Triple Threat along with fellow MNE artist, Blaze Ya Dead Homie.